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Numerical models to evaluate the temperature increase induced by ex vivo microwave thermal ablation

TitleNumerical models to evaluate the temperature increase induced by ex vivo microwave thermal ablation
Publication TypeArticolo su Rivista peer-reviewed
Year of Publication2015
AuthorsCavagnaro, M., Pinto Rosanna, and Lopresto Vanni
JournalPhysics in Medicine and Biology
Volume60
Pagination3287-3311
ISSN00319155
KeywordsAblation, animal, Animals, Antenna feeders, Bio-heat equations, bovine, catheter ablation, Cattle, chemistry, Computer-Assisted, cytology, devices, Electromagnetic Fields, Experimental values, Finite difference method, Heat, High temperature, Hot Temperature, Hybrid materials, Hyperthermia, hyperthermic therapy, Induced, Liver, Local absorptions, mathematical computing, microwave radiation, Microwaves, Models, Numerical analysis, Numerical models, procedures, radiation response, Temperature increase, Temperature increment, Temperature measurement, Theoretical, theoretical model, Thermal ablation, Thermal conductivity, Thermodynamic properties, Tissue, volatilization, Water, Water vaporization
Abstract

Microwave thermal ablation (MTA) therapies exploit the local absorption of an electromagnetic field at microwave (MW) frequencies to destroy unhealthy tissue, by way of a very high temperature increase (about 60 °C or higher). To develop reliable interventional protocols, numerical tools able to correctly foresee the temperature increase obtained in the tissue would be very useful. In this work, different numerical models of the dielectric and thermal property changes with temperature were investigated, looking at the simulated temperature increments and at the size of the achievable zone of ablation. To assess the numerical data, measurement of the temperature increases close to a MTA antenna were performed in correspondence with the antenna feed-point and the antenna cooling system, for increasing values of the radiated power. Results show that models not including the changes of the dielectric and thermal properties can be used only for very low values of the power radiated by the antenna, whereas a good agreement with the experimental values can be obtained up to 20 W if water vaporization is included in the numerical model. Finally, for higher power values, a simulation that dynamically includes the tissue's dielectric and thermal property changes with the temperature should be performed. © 2015 Institute of Physics and Engineering in Medicine.

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URLhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84927651046&doi=10.1088%2f0031-9155%2f60%2f8%2f3287&partnerID=40&md5=b3eeee3a3ac2954f5761923d6d870f2d
DOI10.1088/0031-9155/60/8/3287
Citation KeyCavagnaro20153287